1,520 Alzheimers Headlines
Patricio Reyes M.D., F.A.N.N.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

Barrow Neurological Institute
St. Joseph's Hospital and Medical Center
"2 NEW THERAPIES FOR ALZHEIMER'S"
Produced by MD Health Channel
Executive Editor.....Anne-Merete Robbs
CEO..............Stan Swartz

Dr. Reyes and his team are constantly working on new medicines and new solutions...You will receive news alerts...information on new trials as Dr Reyes announces them!
"2 NEW THERAPIES FOR ALZHEIMER'S"
Patricio Reyes M.D., F.A.N.N.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

St. Joseph's Hospital and Medical Center



DO YOU HAVE ALZHEIMERS?
 
"HELP DR. REYES... IN HIS BATTLE TO FIND A CURE...
.HE NEEDS YOUR HELP:
YOU CAN HELP WIN THE BATTLE FOR A CURE BY JOINING A TRIAL!!"....

Stan Swartz, CEO,
The MD Health Channel



"You'll receive all medication and study based procedures at
no charge

if you qualify for one of the many trials being conducted at Barrow Neurological Institute."
 

"Dr. Reyes Changed My Life"

- John Swartz
92 Years Old
Attorney at Law
"Dr.Reyes Changed My Life "
1:18
"At 92...I had lost my will to live"
5:48
Tips on Aging
2:29
"Dr. Reyes gave me customized health care"
2:09

Patricio Reyes M.D.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

Barrow Neurological Institute

St. Joseph's Hospital and Medical Center
"PRESERVING BRAIN FUNCTIONS "
Runtime: 50:22
Runtime: 50:22
"2 NEW THERAPIES FOR ALZHEIMER'S"
Runtime: 10:27
Runtime: 10:27
ALZHEIMER'S AWARENESS PROGRAMS
Runtime: 5:00
Runtime: 5:00
BIOMEDICAL RESEARCH IN ALZHEIMER'S DISEASE
PDF Document 850 kb

Download Free

4 TALES OF NEUROSURGERY &
A PIANO CONCERT BY DR. SPETZLER...
Plus 2 books written by Survivors for Survivors!
Robert F. Spetzler M.D.
Director, Barrow Neurological Institute

J.N. Harber Chairman of Neurological Surgery

Professor Section of Neurosurgery
University of Arizona
TALES OF NEUROSURGERY:
A pregnant mother..a baby..faith of a husband.. .plus... Cardiac Standstill: cooling the patient to 15 degrees Centigrade!
Lou Grubb Anurism
The young Heros - kids who are confronted with significant medical problems!
2 Patients...confronted with enormous decisions before their surgery...wrote these books to help others!
A 1 MINUTE PIANO CONCERT BY DR. SPETZLER

Michele M. Grigaitis MS, NP
Alzheimer's Disease and Cognitive Disorders Clinic

Barrow Neurological Clinics
COPING WITH DEMENTIA
 
Free Windows Media Player Click

Links
Barrow Neurological Institute

Archives
October 2006  
November 2006  
December 2006  
January 2007  
February 2007  
March 2007  
May 2007  
June 2007  
November 2007  
December 2007  
April 2008  
July 2008  
August 2008  
September 2008  
October 2008  
November 2008  
December 2008  
January 2009  
February 2009  
March 2009  
April 2009  
May 2009  
February 2010  
March 2013  
May 2013  
November 2013  
January 2014  
February 2014  
March 2014  
April 2014  
May 2014  
June 2014  
July 2014  
June 2016  
July 2016  
August 2016  
September 2016  
October 2016  
November 2016  
December 2016  
January 2017  
February 2017  
March 2017  
April 2017  
May 2017  
June 2017  
July 2017  
August 2017  
September 2017  
October 2017  
November 2017  
December 2017  
January 2018  
February 2018  
March 2018  
April 2018  
May 2018  
June 2018  
July 2018  

This page is powered by Blogger. Isn't yours?

Monday, February 20, 2017

 

Understanding the Aging Brain


New research from Li-Huei Tsai’s lab suggests the immune system may play a role in Alzheimer’s disease.  
Photo: M. Scott Brauer

FOR DECADES, Alzheimer’s disease research has focused on neurons. That’s logical: after all, it’s our brain cells that become diseased, causing a decline in our memory and ability to think. But new research from Li- Tsai’s lab suggests the immune system may also play a role in Alzheimer’s.

The discovery is welcome news since, so far, clinical trials of Alzheimer’s drugs that target neurons have been unsuccessful. “We really need a portfolio of targets,” says Tsai, Picower Professor of Neuroscience and Director of the Picower Institute  Learning and Memory.

About 35 million people worldwide have dementia. More than 5 million Americans have Alzheimer’s disease. And the numbers are expected to rise in the coming decades as the population ages. Also, because there are no effective therapies for these diseases, the costs of care are high. In fact, in the US, the cost of Alzheimer’s disease care exceeds all other health care costs.

If we don’t address the need for treatment now, the economic burden is going to be unbearable soon,” says Tsai, who is taking on this challenge.

Tsai is leading the Aging Brain Initiative. This collaborative effort at MIT focuses on brain aging because it is a risk factor that spans all forms of dementia, but how it influences these diseases is unknown. “We still don’t quite understand how dementia begins and progresses,” says Tsai. “This contributes to the fact that we don’t have a whole lot of options when it comes to drugs.”

The Aging Brain Initiative brings together an accomplished group of MIT researchers, including neuroscientists, biologists, computer scientists, and engineers, to leverage MIT’s strengths to build foundational brain-aging knowledge and rapidly bring solutions to the clinic. The Initiative’s four-pronged approach will identify aging biomarkers, develop circuit-specific therapeutics, explore personalized molecular medicine, and identify strategies to promote healthy brain aging.

Other founding members include: Edward Boyden, associate professor of Biological Engineering and Brain and Cognitive Sciences; Emery Brown, Edward Hood Taplin Professor of Medical Engineering and of Computational Neuroscience; Leonard Guarente, Novartis Professor of Biology; Robert Horvitz, David H. Koch Professor of Biology; Susan Lindquist, Professor of Biology; and Susumu Tonegawa, Picower Professor of Biology and Neuroscience.

Tsai is also co-associate director of the new Paul F. Glenn Center for Science of Aging Research at MIT, which will leverage the strengths of MIT biologists, neuroscientists, and cancer researchers to understand aging.

Tsai’s discovery that the immune system may play a role in Alzheimer’s disease is an example of how fundamental research can drive new ideas for clinical therapies. The team investigated brain epigenetics, changes in cellular interactions with DNA that redirect gene behavior. This work led to the discovery of misbehaving immune cells in the brains of mice engineered to mimic Alzheimer’s. “Now we realize the immune system plays an important role, and possibly a causative role in Alzheimer’s disease,” she says.

Tsai is already acting on these findings, which were published in Nature last winter. One effort is sharply focused on screening for drugs that might correct immune cell behavior.

Another effort, in collaboration with the Broad Institute, will look at the individual gene expression profiles of a wide range of immune cells. This analysis, called single-cell RNA sequencing, will provide Tsai with an extraordinarily detailed view of how many different types of immune cells there are in the brain. “There’s a sense that there are beneficial immune cells and bad immune cells in the brain,” she says. “So we say, how many different kinds are there? We need to get to know them better before we know the best way forward.”

Story Source: The above story is based on materials provided by SPECTRUM
Note: Materials may be edited for content and length