1,520 Alzheimers Headlines
Patricio Reyes M.D., F.A.N.N.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

Barrow Neurological Institute
St. Joseph's Hospital and Medical Center
"2 NEW THERAPIES FOR ALZHEIMER'S"
Produced by MD Health Channel
Executive Editor.....Anne-Merete Robbs
CEO..............Stan Swartz

Dr. Reyes and his team are constantly working on new medicines and new solutions...You will receive news alerts...information on new trials as Dr Reyes announces them!
"2 NEW THERAPIES FOR ALZHEIMER'S"
Patricio Reyes M.D., F.A.N.N.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

St. Joseph's Hospital and Medical Center



DO YOU HAVE ALZHEIMERS?
 
"HELP DR. REYES... IN HIS BATTLE TO FIND A CURE...
.HE NEEDS YOUR HELP:
YOU CAN HELP WIN THE BATTLE FOR A CURE BY JOINING A TRIAL!!"....

Stan Swartz, CEO,
The MD Health Channel



"You'll receive all medication and study based procedures at
no charge

if you qualify for one of the many trials being conducted at Barrow Neurological Institute."
 

"Dr. Reyes Changed My Life"

- John Swartz
92 Years Old
Attorney at Law
"Dr.Reyes Changed My Life "
1:18
"At 92...I had lost my will to live"
5:48
Tips on Aging
2:29
"Dr. Reyes gave me customized health care"
2:09

Patricio Reyes M.D.
Director, Traumatic Brain Injury, Alzheimer's Disease & Cognitive Disorders Clinics; Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association

Barrow Neurological Institute

St. Joseph's Hospital and Medical Center
"PRESERVING BRAIN FUNCTIONS "
Runtime: 50:22
Runtime: 50:22
"2 NEW THERAPIES FOR ALZHEIMER'S"
Runtime: 10:27
Runtime: 10:27
ALZHEIMER'S AWARENESS PROGRAMS
Runtime: 5:00
Runtime: 5:00
BIOMEDICAL RESEARCH IN ALZHEIMER'S DISEASE
PDF Document 850 kb

Download Free

4 TALES OF NEUROSURGERY &
A PIANO CONCERT BY DR. SPETZLER...
Plus 2 books written by Survivors for Survivors!
Robert F. Spetzler M.D.
Director, Barrow Neurological Institute

J.N. Harber Chairman of Neurological Surgery

Professor Section of Neurosurgery
University of Arizona
TALES OF NEUROSURGERY:
A pregnant mother..a baby..faith of a husband.. .plus... Cardiac Standstill: cooling the patient to 15 degrees Centigrade!
Lou Grubb Anurism
The young Heros - kids who are confronted with significant medical problems!
2 Patients...confronted with enormous decisions before their surgery...wrote these books to help others!
A 1 MINUTE PIANO CONCERT BY DR. SPETZLER

Michele M. Grigaitis MS, NP
Alzheimer's Disease and Cognitive Disorders Clinic

Barrow Neurological Clinics
COPING WITH DEMENTIA
 
Free Windows Media Player Click

Links
Barrow Neurological Institute

Archives
October 2006  
November 2006  
December 2006  
January 2007  
February 2007  
March 2007  
May 2007  
June 2007  
November 2007  
December 2007  
April 2008  
July 2008  
August 2008  
September 2008  
October 2008  
November 2008  
December 2008  
January 2009  
February 2009  
March 2009  
April 2009  
May 2009  
February 2010  
March 2013  
May 2013  
November 2013  
January 2014  
February 2014  
March 2014  
April 2014  
May 2014  
June 2014  
July 2014  
June 2016  
July 2016  
August 2016  
September 2016  
October 2016  
November 2016  
December 2016  
January 2017  
February 2017  
March 2017  
April 2017  
May 2017  
June 2017  
July 2017  
August 2017  
September 2017  
October 2017  
November 2017  
December 2017  
January 2018  
February 2018  
March 2018  
April 2018  
May 2018  
June 2018  
July 2018  
August 2018  
September 2018  
October 2018  
November 2018  
December 2018  
January 2019  
February 2019  
March 2019  
April 2019  
May 2019  
June 2019  
July 2019  
August 2019  
September 2019  
October 2019  
November 2019  
December 2019  
January 2020  
February 2020  
March 2020  
April 2020  
May 2020  
June 2020  
July 2020  
August 2020  
September 2020  
October 2020  
November 2020  
December 2020  
January 2021  
February 2021  
March 2021  
April 2021  
May 2021  
June 2021  
July 2021  
August 2021  
September 2021  
October 2021  
November 2021  
December 2021  
January 2022  
February 2022  
March 2022  
April 2022  
May 2022  
June 2022  
July 2022  
August 2022  
September 2022  
October 2022  
November 2022  
December 2022  
January 2023  
February 2023  
March 2023  
April 2023  
May 2023  
June 2023  
July 2023  
August 2023  
September 2023  
October 2023  
November 2023  
December 2023  
January 2024  
February 2024  
March 2024  

This page is powered by Blogger. Isn't yours?

Monday, July 18, 2016

 

3-D imaging reveals unexpected arrangement of plaques in Alzheimer's-afflicted brains































This image shows a triple stain of vasculature, glia cells, and plaques in the brain.
Credit: Dr. Thomas Liebmann, The Rockefeller University

Rockefeller University researchers have used a recently-developed imaging technique that makes tissue transparent to visualize brain tissue from deceased patients with Alzheimer's disease, exposing nonrandom, higher-order structures of beta amyloid plaques--sticky clumps of a toxic protein typically found in the brains of people with Alzheimer's. The findings appear July 14 in Cell Reports.

"Until now, we've been studying the brain using 2D slices; and I've always felt that was inadequate, because it's a complex, 3D structure with many interlocking components," says senior author Marc Flajolet, an assistant professor in the Laboratory of Molecular and Cellular Neuroscience at The Rockefeller University. "Not only was slicing time consuming and 3D reconstruction laborious when not erroneous, it gave us a limited view. We needed some way to look at this 3D structure in all of its dimensions without preliminary slicing of the brain."

The researchers wanted to go beyond the traditional 3D brain imaging (e.g., PET or fMRI scans), which show brain activity in a broad way, but have a low resolution overall. To circumvent this, the research team turned to a recently-developed method, called "iDISCO." Here, brains are soaked in a solution that imbue the fats within it with a charge, before being exposed to an electrical field with an opposite charge, which behaves like a magnet, forcing all of the fat out of the brain tissue.

The result, says Flajolet, is a brain that is hard and transparent, almost "like glass," which allowed the researchers to see the amyloid plaques in full detail and in 3D, in a full mouse brain hemisphere, as well as in small blocks of human brain tissue.

"In mouse models, plaques are rather small, homogenous in size and shape, and not grouped in any specific way," says Flajolet. "But in the human brain, we were seeing more heterogeneity, larger plaques and these new, complex patterns." These structures, called TAPs (three dimensional amyloid patterns) may have implications for the future of Alzheimer's disease treatment, he says. By comparing doctor's reports of a patient's symptoms with images of the patient's brain post-mortem, they may be able to classify different categories of Alzheimer's disease.

"There are people with brains full of plaques and no dementia at all," he says, "and there are those with brains free of plaques with many of the symptoms." In light of that, the way that current clinical trials view the disease--namely, that there is one category--might be incorrect, he says. It's possible that current drugs may be beneficial only for a subset of Alzheimer patients, but we have no way to distinguish them at this day.

Story Source: The above story is based on materials provided by SCIENCEDAILY
Note: Materials may be edited for content and length
Click here to read more