Anne Robbs, Editor

Great benefit of wine!! 
Gotta read this...

"Resveratrol improves the health of mice on a high-fat diet and increases life span."

It was always postulated that resveratrol had benefits, but the question was proving the mechanisms involved and moving beyond the realm of "old wives tale" and into the science of the process.

Understanding how resveratrol works would move pharmacists forwards into the possibilities of an anti-aging drug, although most people would probably prefer to pop a cork rather than a bottle of pills, there are many diseases such as alzheimer's that could potentially be retarded with more focused treatment. It seems that mice lacking the longevity gene known as SIRT1, don't seem to show benefits from resveratrol.

Although its actions had in the past been attributed to its action on the SIRT1 gene, the naturally occurring molecule in red wine seems to have other effects on dozens of proteins and previous evidence had pointed researchers towards its effect on another gene known as AMPK. This research in mice, yeast, worms and flies, called into question the intelligence of creating an SIRT1 targeting drug, since resveratrol seemed to have other benefits. Due to these findings, Pharma company Sirtris halted its 2011 clinic trial of resveratrol.

READ MORE