Executive Editor.....Anne-Merete Robbs
CEO..............Stan Swartz
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Dr. Reyes and his team are constantly working on new medicines and new solutions...You will receive news alerts...information on new trials as Dr Reyes announces them! |
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"2 NEW THERAPIES FOR ALZHEIMER'S"
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Patricio Reyes M.D., F.A.N.N.
Director, Traumatic Brain Injury,
Alzheimer's Disease & Cognitive Disorders Clinics;
Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association
St. Joseph's Hospital and Medical Center |
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DO YOU HAVE ALZHEIMERS?
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"HELP DR. REYES... IN HIS BATTLE TO FIND A CURE...
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YOU CAN HELP WIN THE BATTLE FOR A CURE BY JOINING A TRIAL!!"....
Stan Swartz, CEO,
The MD Health Channel
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"You'll receive all medication and study based procedures at
no charge
if you qualify for one of the many trials being conducted at Barrow Neurological Institute." |
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Patricio Reyes M.D.
Director, Traumatic Brain Injury,
Alzheimer's Disease & Cognitive Disorders Clinics;
Phoenix, AZ; Chief Medical Officer, Retired NFL Players Association
Barrow Neurological Institute
St. Joseph's Hospital and Medical Center |
"PRESERVING BRAIN FUNCTIONS " |
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Runtime: 50:22 |
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Runtime: 50:22 |
"2 NEW THERAPIES FOR ALZHEIMER'S" |
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Runtime: 10:27 |
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Runtime: 10:27 |
ALZHEIMER'S AWARENESS PROGRAMS |
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Runtime: 5:00 |
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Runtime: 5:00 |
BIOMEDICAL RESEARCH IN ALZHEIMER'S DISEASE |
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PDF Document 850 kb |
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4 TALES OF NEUROSURGERY &
A PIANO CONCERT BY DR. SPETZLER...
Plus 2 books written by Survivors for Survivors! |
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Robert F. Spetzler M.D.
Director, Barrow Neurological Institute
J.N. Harber Chairman of Neurological Surgery
Professor Section of Neurosurgery
University of Arizona |
TALES OF NEUROSURGERY: |
A pregnant mother..a baby..faith of a husband.. .plus... Cardiac Standstill: cooling the patient to 15 degrees Centigrade!
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Lou Grubb Anurism
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The young Heros - kids who are confronted with significant medical problems!
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2 Patients...confronted with enormous decisions before their surgery...wrote these books to help others!
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A 1 MINUTE PIANO CONCERT BY DR. SPETZLER
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Michele M. Grigaitis MS, NP
Alzheimer's Disease and Cognitive Disorders Clinic
Barrow Neurological Clinics |
COPING WITH DEMENTIA |
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Sunday, March 5, 2017
On drugs for Alzheimer’s
Jynto: Wikimedia Commons
The Dental Institute of King’s College London discovered that tideglusib, an experimental drug designed to treat Alzheimer’s, can also be used to help teeth regenerate.
Tideglusib is a GSK-3 beta inhibitor, which means it binds to receptors on Glycogen Synthase Kinase-3 molecules in the brain and prevents them from carrying out their intended function. One function of GSK-3 is that it targets cells for destruction after reacting with the protein beta-catenin. In Alzheimer’s patients, the brain contains too much beta-catenin (among other molecules) and therefore is in excess, able to react more with GSK-3 and induce degradation in far too many cells. When tideglusib binds to these receptors instead, it is no longer possible for beta-catenin to bind.
However, another function of GSK-3 is that it prevents dentine — the bone-like, calcium-heavy tissue in human teeth — from growing from stem cells after teeth have been damaged by cavities. Therefore, when a dental patient with cavities takes the drug, their GSK-3 receptors are also inhibited and their brain no longer produces a signal telling their teeth stem cells not to become dentine cells. Dentine begins to grow again in the body, and teeth are able to heal themselves, filling the entire cavity gap and behaving just the same as the patient’s original teeth.
Although this drug showed definite potential as an Alzheimer’s treatment, now, when researching tideglusib, almost every search result is related to its newfound potential as a tooth repair drug. Which is definitely a fascinating concept — the idea that the same chemical can have two separate, incredibly helpful effects on the body, both of them seemingly unrelated, can’t just be an amazing coincidence.
This could potentially teach us a lot about how the brain works, since it’s possible that the same process that stops damaged teeth from being able to repair themselves also stops certain neural pathways in Alzheimer’s patients from being able to repair themselves.
But even though there are incredible research implications here, I don’t think we should lose sight of the original purpose of the drug. Over 5 million Americans currently suffer from Alzheimer’s and as the cause of the disease is unknown, it’s very difficult to prevent. It also affects the patient’s entire life after diagnosis as well as the lives of those close to them, who then become their caregivers. The illness is chronic and currently untreatable, with quality of life dropping sharply for sufferers in the later stages.
On the other hand, tooth decay is something we already know plenty about, and there’s a lot of education and free information available discussing how to prevent it. Avoiding sugary foods plus brushing and flossing your teeth dramatically reduces the risks of tooth decay. Even when teeth do develop cavities and fillings are required, having a filling inserted is a relatively painless process, taking just a few minutes under a local anaesthetic. Fillings may need to be replaced if they begin to cause pain or discomfort, but this usually does not happen for many years after the original filling, and is certainly not life threatening. The cost of fillings is almost nothing in comparison to the many tests, doctors’ visits and drugs required by an Alzheimer’s patient.
Story
Source: The
above story is based on materials provided by THETRIANGLE
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